Gene information
Official symbol EDN1
Official full name endothelin 1
Gene type protein-coding gene
Chromosome6p24.1
Alias symbolET1
Gene familyEndothelins
Resources
Entrez Gene 1906
HGNC HGNC:3176
Ensembl ENSG00000078401
Vega OTTHUMG00000014266
UCSC uc003nae.5
GO terms: 328 records
GO Description Category LogP Number of genes Detail
GO:0000302 response to reactive oxygen species GO Biological Processes -13.4775134 34 More
GO:0001101 response to acid chemical GO Biological Processes -10.2965313 26 More
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0001525 angiogenesis GO Biological Processes -32.8794581 74 More
GO:0001558 regulation of cell growth GO Biological Processes -19.1123936 65 More
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001569 branching involved in blood vessel morphogenesis GO Biological Processes -5.46031079 9 More
GO:0001664 G protein-coupled receptor binding GO Molecular Functions -22.7408810 35 More
GO:0001666 response to hypoxia GO Biological Processes -40.6131384 77 More
GO:0001667 ameboidal-type cell migration GO Biological Processes -17.0771232 40 More
GO:0001701 in utero embryonic development GO Biological Processes -8.76987260 44 More
GO:0001755 neural crest cell migration GO Biological Processes -8.06132628 15 More
GO:0001763 morphogenesis of a branching structure GO Biological Processes -11.2402819 31 More
GO:0001775 cell activation GO Biological Processes -43.3738118 71 More
GO:0001837 epithelial to mesenchymal transition GO Biological Processes -7.70350405 17 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0001959 regulation of cytokine-mediated signaling pathway GO Biological Processes -13.0991884 33 More
GO:0001961 positive regulation of cytokine-mediated signaling pathway GO Biological Processes -3.95887136 6 More
GO:0001990 regulation of systemic arterial blood pressure by hormone GO Biological Processes -7.86007212 8 More
GO:0002009 morphogenesis of an epithelium GO Biological Processes -21.4354199 71 More
GO:0002027 regulation of heart rate GO Biological Processes -9.97103962 23 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002685 regulation of leukocyte migration GO Biological Processes -36.943236 43 More
GO:0002687 positive regulation of leukocyte migration GO Biological Processes -31.0737422 33 More
GO:0002688 regulation of leukocyte chemotaxis GO Biological Processes -31.6279962 32 More
GO:0002690 positive regulation of leukocyte chemotaxis GO Biological Processes -28.1480961 27 More
GO:0002790 peptide secretion GO Biological Processes -5.12832495 12 More
GO:0003002 regionalization GO Biological Processes -7.48750854 38 More
GO:0003007 heart morphogenesis GO Biological Processes -18.8519524 49 More
GO:0003012 muscle system process GO Biological Processes -27.3938503 63 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003014 renal system process GO Biological Processes -10.4348518 24 More
GO:0003015 heart process GO Biological Processes -12.3962712 26 More
GO:0003073 regulation of systemic arterial blood pressure GO Biological Processes -22.2238525 34 More
GO:0003151 outflow tract morphogenesis GO Biological Processes -7.88412825 17 More
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0005179 hormone activity GO Molecular Functions -33.3562443 33 More
GO:0005788 endoplasmic reticulum lumen GO Cellular Components -47.2996164 57 More
GO:0005791 rough endoplasmic reticulum GO Cellular Components -2.39543019 5 More
GO:0006468 protein phosphorylation GO Biological Processes -5.36604576 56 More
GO:0006801 superoxide metabolic process GO Biological Processes -5.35296451 10 More
GO:0006816 calcium ion transport GO Biological Processes -5.55009887 27 More
GO:0006873 cellular ion homeostasis GO Biological Processes -10.3574947 26 More
GO:0006875 cellular metal ion homeostasis GO Biological Processes -10.3879696 23 More
GO:0006935 chemotaxis GO Biological Processes -33.1726887 55 More
GO:0006936 muscle contraction GO Biological Processes -17.3443769 27 More
GO:0006937 regulation of muscle contraction GO Biological Processes -20.8046481 43 More
GO:0006939 smooth muscle contraction GO Biological Processes -6.47455620 13 More
GO:0006940 regulation of smooth muscle contraction GO Biological Processes -12.9613663 21 More
GO:0006979 response to oxidative stress GO Biological Processes -17.6147653 58 More
GO:0007005 mitochondrion organization GO Biological Processes -2.05283627 29 More
GO:0007088 regulation of mitotic nuclear division GO Biological Processes -2.33218274 6 More
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO Biological Processes -9.16710904 33 More
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway GO Biological Processes -11.6592522 24 More
GO:0007204 positive regulation of cytosolic calcium ion concentration GO Biological Processes -15.6883547 39 More
GO:0007276 gamete generation GO Biological Processes -2.03816629 18 More
GO:0007411 axon guidance GO Biological Processes -2.45312404 19 More
GO:0007507 heart development GO Biological Processes -29.3002557 91 More
GO:0007568 aging GO Biological Processes -23.5429582 29 More
GO:0007589 body fluid secretion GO Biological Processes -11.5155091 20 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008016 regulation of heart contraction GO Biological Processes -27.6827716 55 More
GO:0008217 regulation of blood pressure GO Biological Processes -35.2019435 60 More
GO:0008277 regulation of G protein-coupled receptor signaling pathway GO Biological Processes -5.69311965 11 More
GO:0008361 regulation of cell size GO Biological Processes -4.6524989 21 More
GO:0009410 response to xenobiotic stimulus GO Biological Processes -32.6021211 82 More
GO:0009612 response to mechanical stimulus GO Biological Processes -18.7627330 44 More
GO:0009617 response to bacterium GO Biological Processes -52.1760880 83 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009792 embryo development ending in birth or egg hatching GO Biological Processes -12.9988944 72 More
GO:0009914 hormone transport GO Biological Processes -6.35710158 16 More
GO:0009953 dorsal/ventral pattern formation GO Biological Processes -2.60370974 10 More
GO:0010035 response to inorganic substance GO Biological Processes -29.1720710 89 More
GO:0010038 response to metal ion GO Biological Processes -20.5090881 61 More
GO:0010460 positive regulation of heart rate GO Biological Processes -6.02792411 9 More
GO:0010594 regulation of endothelial cell migration GO Biological Processes -41.8778170 72 More
GO:0010595 positive regulation of endothelial cell migration GO Biological Processes -28.3201829 45 More
GO:0010611 regulation of cardiac muscle hypertrophy GO Biological Processes -13.5611908 22 More
GO:0010632 regulation of epithelial cell migration GO Biological Processes -42.8870194 81 More
GO:0010634 positive regulation of epithelial cell migration GO Biological Processes -29.2566722 52 More
GO:0010638 positive regulation of organelle organization GO Biological Processes -6.49207636 47 More
GO:0010660 regulation of muscle cell apoptotic process GO Biological Processes -26.1774267 35 More
GO:0010827 regulation of glucose transmembrane transport GO Biological Processes -18.4601079 28 More
GO:0014033 neural crest cell differentiation GO Biological Processes -12.2997127 24 More
GO:0014075 response to amine GO Biological Processes -4.21089449 9 More
GO:0014743 regulation of muscle hypertrophy GO Biological Processes -14.1608908 23 More
GO:0014823 response to activity GO Biological Processes -19.5783025 27 More
GO:0014829 vascular associated smooth muscle contraction GO Biological Processes -5.72938190 7 More
GO:0016049 cell growth GO Biological Processes -4.37315767 14 More
GO:0016055 Wnt signaling pathway GO Biological Processes -5.19226517 28 More
GO:0019233 sensory perception of pain GO Biological Processes -10.7642352 20 More
GO:0019722 calcium-mediated signaling GO Biological Processes -11.6647584 29 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0019932 second-messenger-mediated signaling GO Biological Processes -19.1717114 46 More
GO:0021675 nerve development GO Biological Processes -3.85527067 12 More
GO:0021700 developmental maturation GO Biological Processes -12.5205714 23 More
GO:0022898 regulation of transmembrane transporter activity GO Biological Processes -11.1988499 41 More
GO:0023061 signal release GO Biological Processes -5.50151396 21 More
GO:0030003 cellular cation homeostasis GO Biological Processes -9.22969208 24 More
GO:0030193 regulation of blood coagulation GO Biological Processes -37.6853179 30 More
GO:0030195 negative regulation of blood coagulation GO Biological Processes -29.1940441 22 More
GO:0030307 positive regulation of cell growth GO Biological Processes -13.7154299 34 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0031175 neuron projection development GO Biological Processes -7.36986002 58 More
GO:0031644 regulation of nervous system process GO Biological Processes -8.22607591 24 More
GO:0031960 response to corticosteroid GO Biological Processes -20.1789519 26 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032103 positive regulation of response to external stimulus GO Biological Processes -58.7273809 118 More
GO:0032303 regulation of icosanoid secretion GO Biological Processes -5.74582458 8 More
GO:0032305 positive regulation of icosanoid secretion GO Biological Processes -5.92579036 8 More
GO:0032368 regulation of lipid transport GO Biological Processes -34.5766289 54 More
GO:0032409 regulation of transporter activity GO Biological Processes -16.9480646 53 More
GO:0032412 regulation of ion transmembrane transporter activity GO Biological Processes -9.90560995 38 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0032535 regulation of cellular component size GO Biological Processes -4.60941253 33 More
GO:0032870 cellular response to hormone stimulus GO Biological Processes -24.7707938 79 More
GO:0032890 regulation of organic acid transport GO Biological Processes -14.1608908 23 More
GO:0032892 positive regulation of organic acid transport GO Biological Processes -8.61037442 14 More
GO:0032940 secretion by cell GO Biological Processes -8.42144465 43 More
GO:0032956 regulation of actin cytoskeleton organization GO Biological Processes -4.25470878 32 More
GO:0032970 regulation of actin filament-based process GO Biological Processes -7.72273150 43 More
GO:0032989 cellular component morphogenesis GO Biological Processes -4.92421328 47 More
GO:0033574 response to testosterone GO Biological Processes -7.37064762 8 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0034341 response to interferon-gamma GO Biological Processes -10.8524889 26 More
GO:0034599 cellular response to oxidative stress GO Biological Processes -11.6255265 36 More
GO:0034612 response to tumor necrosis factor GO Biological Processes -24.4651326 32 More
GO:0034614 cellular response to reactive oxygen species GO Biological Processes -9.93259803 24 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034764 positive regulation of transmembrane transport GO Biological Processes -18.2616571 46 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0035050 embryonic heart tube development GO Biological Processes -8.08177140 18 More
GO:0035051 cardiocyte differentiation GO Biological Processes -18.7205561 33 More
GO:0035094 response to nicotine GO Biological Processes -8.07167727 14 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035270 endocrine system development GO Biological Processes -10.2307745 25 More
GO:0035809 regulation of urine volume GO Biological Processes -2.60562540 3 More
GO:0035813 regulation of renal sodium excretion GO Biological Processes -6.79568546 6 More
GO:0035994 response to muscle stretch GO Biological Processes -4.25041921 7 More
GO:0036293 response to decreased oxygen levels GO Biological Processes -40.9544531 79 More
GO:0036294 cellular response to decreased oxygen levels GO Biological Processes -14.5279047 32 More
GO:0040007 growth GO Biological Processes -14.0580178 53 More
GO:0040008 regulation of growth GO Biological Processes -30.7609323 104 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042310 vasoconstriction GO Biological Processes -9.70418585 13 More
GO:0042330 taxis GO Biological Processes -33.0828571 55 More
GO:0042391 regulation of membrane potential GO Biological Processes -15.0641346 59 More
GO:0042481 regulation of odontogenesis GO Biological Processes -5.69256069 5 More
GO:0042542 response to hydrogen peroxide GO Biological Processes -8.84445919 13 More
GO:0042554 superoxide anion generation GO Biological Processes -3.67847337 4 More
GO:0043009 chordate embryonic development GO Biological Processes -11.8113315 68 More
GO:0043200 response to amino acid GO Biological Processes -9.16129691 23 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043405 regulation of MAP kinase activity GO Biological Processes -18.9267681 42 More
GO:0043406 positive regulation of MAP kinase activity GO Biological Processes -13.8261343 18 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043434 response to peptide hormone GO Biological Processes -26.1739008 69 More
GO:0043502 regulation of muscle adaptation GO Biological Processes -16.8828965 29 More
GO:0043507 positive regulation of JUN kinase activity GO Biological Processes -1.72986901 3 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0044062 regulation of excretion GO Biological Processes -7.89562883 7 More
GO:0044070 regulation of anion transport GO Biological Processes -12.6410846 24 More
GO:0044703 multi-organism reproductive process GO Biological Processes -20.5752550 28 More
GO:0044706 multi-multicellular organism process GO Biological Processes -20.0155761 28 More
GO:0045165 cell fate commitment GO Biological Processes -15.5778047 44 More
GO:0045321 leukocyte activation GO Biological Processes -25.4958219 48 More
GO:0045428 regulation of nitric oxide biosynthetic process GO Biological Processes -19.2075726 26 More
GO:0045429 positive regulation of nitric oxide biosynthetic process GO Biological Processes -13.6962150 18 More
GO:0045823 positive regulation of heart contraction GO Biological Processes -10.6953794 15 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0045927 positive regulation of growth GO Biological Processes -20.3035639 52 More
GO:0045933 positive regulation of muscle contraction GO Biological Processes -10.2635447 16 More
GO:0045987 positive regulation of smooth muscle contraction GO Biological Processes -5.46031079 9 More
GO:0046620 regulation of organ growth GO Biological Processes -13.2396968 26 More
GO:0046622 positive regulation of organ growth GO Biological Processes -9.67012229 16 More
GO:0046879 hormone secretion GO Biological Processes -6.27678757 15 More
GO:0046887 positive regulation of hormone secretion GO Biological Processes -9.61661717 24 More
GO:0046903 secretion GO Biological Processes -18.5147167 70 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048469 cell maturation GO Biological Processes -5.75704415 12 More
GO:0048514 blood vessel morphogenesis GO Biological Processes -39.8784810 93 More
GO:0048545 response to steroid hormone GO Biological Processes -20.1914989 32 More
GO:0048562 embryonic organ morphogenesis GO Biological Processes -8.59880895 37 More
GO:0048568 embryonic organ development GO Biological Processes -17.1204114 64 More
GO:0048588 developmental cell growth GO Biological Processes -4.47857706 14 More
GO:0048589 developmental growth GO Biological Processes -14.0580178 53 More
GO:0048598 embryonic morphogenesis GO Biological Processes -22.1253699 83 More
GO:0048638 regulation of developmental growth GO Biological Processes -23.5012496 63 More
GO:0048639 positive regulation of developmental growth GO Biological Processes -14.4198804 35 More
GO:0048660 regulation of smooth muscle cell proliferation GO Biological Processes -48.6624498 69 More
GO:0048661 positive regulation of smooth muscle cell proliferation GO Biological Processes -29.0732096 40 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0048732 gland development GO Biological Processes -26.3979320 74 More
GO:0048754 branching morphogenesis of an epithelial tube GO Biological Processes -10.2965313 26 More
GO:0048762 mesenchymal cell differentiation GO Biological Processes -16.1250183 37 More
GO:0048844 artery morphogenesis GO Biological Processes -13.4119116 22 More
GO:0048863 stem cell differentiation GO Biological Processes -16.2106470 36 More
GO:0050801 ion homeostasis GO Biological Processes -12.0812968 60 More
GO:0050804 modulation of chemical synaptic transmission GO Biological Processes -15.2260557 60 More
GO:0050818 regulation of coagulation GO Biological Processes -40.0839917 32 More
GO:0050819 negative regulation of coagulation GO Biological Processes -31.8350192 24 More
GO:0050878 regulation of body fluid levels GO Biological Processes -57.9546976 69 More
GO:0050886 endocrine process GO Biological Processes -9.16554283 10 More
GO:0050920 regulation of chemotaxis GO Biological Processes -36.3269885 43 More
GO:0050921 positive regulation of chemotaxis GO Biological Processes -35.4880405 36 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051048 negative regulation of secretion GO Biological Processes -20.2278199 42 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
GO:0051091 positive regulation of DNA-binding transcription factor activity GO Biological Processes -17.7436786 49 More
GO:0051153 regulation of striated muscle cell differentiation GO Biological Processes -11.0877013 23 More
GO:0051216 cartilage development GO Biological Processes -10.5011549 17 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0051341 regulation of oxidoreductase activity GO Biological Processes -18.1249013 32 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051353 positive regulation of oxidoreductase activity GO Biological Processes -12.6682372 20 More
GO:0051384 response to glucocorticoid GO Biological Processes -16.9609899 22 More
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway GO Biological Processes -4.39154198 8 More
GO:0051493 regulation of cytoskeleton organization GO Biological Processes -3.52271067 40 More
GO:0051495 positive regulation of cytoskeleton organization GO Biological Processes -3.67944181 20 More
GO:0051592 response to calcium ion GO Biological Processes -7.43492702 23 More
GO:0051783 regulation of nuclear division GO Biological Processes -1.91099987 6 More
GO:0051899 membrane depolarization GO Biological Processes -3.15848951 8 More
GO:0055065 metal ion homeostasis GO Biological Processes -12.9426258 29 More
GO:0055074 calcium ion homeostasis GO Biological Processes -10.3600555 19 More
GO:0055080 cation homeostasis GO Biological Processes -11.5718912 30 More
GO:0055082 cellular chemical homeostasis GO Biological Processes -17.6289728 71 More
GO:0060037 pharyngeal system development GO Biological Processes -4.73205562 8 More
GO:0060070 canonical Wnt signaling pathway GO Biological Processes -4.33026410 13 More
GO:0060485 mesenchyme development GO Biological Processes -18.0238 46 More
GO:0060560 developmental growth involved in morphogenesis GO Biological Processes -3.88675190 15 More
GO:0060562 epithelial tube morphogenesis GO Biological Processes -17.7630248 53 More
GO:0060759 regulation of response to cytokine stimulus GO Biological Processes -13.7003447 35 More
GO:0060760 positive regulation of response to cytokine stimulus GO Biological Processes -4.64741860 7 More
GO:0060840 artery development GO Biological Processes -12.7697342 25 More
GO:0061041 regulation of wound healing GO Biological Processes -35.8633788 36 More
GO:0061045 negative regulation of wound healing GO Biological Processes -28.2986689 25 More
GO:0061138 morphogenesis of a branching epithelium GO Biological Processes -11.1441029 30 More
GO:0061307 cardiac neural crest cell differentiation involved in heart development GO Biological Processes -5.39331932 6 More
GO:0061308 cardiac neural crest cell development involved in heart development GO Biological Processes -5.39331932 6 More
GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis GO Biological Processes -6.38728364 6 More
GO:0061448 connective tissue development GO Biological Processes -12.1108226 21 More
GO:0062197 cellular response to chemical stress GO Biological Processes -14.0979689 44 More
GO:0070301 cellular response to hydrogen peroxide GO Biological Processes -5.36006230 13 More
GO:0070371 ERK1 and ERK2 cascade GO Biological Processes -5.02945267 6 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0070542 response to fatty acid GO Biological Processes -13.2686457 21 More
GO:0070555 response to interleukin-1 GO Biological Processes -18.9736890 36 More
GO:0070588 calcium ion transmembrane transport GO Biological Processes -2.54626507 17 More
GO:0070848 response to growth factor GO Biological Processes -40.6139195 102 More
GO:0071241 cellular response to inorganic substance GO Biological Processes -4.23170629 23 More
GO:0071248 cellular response to metal ion GO Biological Processes -4.26641514 21 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:0071347 cellular response to interleukin-1 GO Biological Processes -16.1002741 19 More
GO:0071356 cellular response to tumor necrosis factor GO Biological Processes -22.5666334 29 More
GO:0071363 cellular response to growth factor stimulus GO Biological Processes -39.8883675 98 More
GO:0071375 cellular response to peptide hormone stimulus GO Biological Processes -15.9961580 44 More
GO:0071383 cellular response to steroid hormone stimulus GO Biological Processes -3.35454241 16 More
GO:0071384 cellular response to corticosteroid stimulus GO Biological Processes -3.75773024 6 More
GO:0071385 cellular response to glucocorticoid stimulus GO Biological Processes -3.19400389 5 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0071398 cellular response to fatty acid GO Biological Processes -4.09043632 8 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0071453 cellular response to oxygen levels GO Biological Processes -14.8173809 34 More
GO:0071456 cellular response to hypoxia GO Biological Processes -14.4449186 31 More
GO:0071466 cellular response to xenobiotic stimulus GO Biological Processes -9.33788411 28 More
GO:0071548 response to dexamethasone GO Biological Processes -4.38480829 9 More
GO:0071559 response to transforming growth factor beta GO Biological Processes -17.0634996 37 More
GO:0071560 cellular response to transforming growth factor beta stimulus GO Biological Processes -16.8909657 36 More
GO:0071622 regulation of granulocyte chemotaxis GO Biological Processes -10.3031127 11 More
GO:0071624 positive regulation of granulocyte chemotaxis GO Biological Processes -4.01585848 7 More
GO:0071695 anatomical structure maturation GO Biological Processes -11.1692541 20 More
GO:0071900 regulation of protein serine/threonine kinase activity GO Biological Processes -19.5794055 63 More
GO:0071902 positive regulation of protein serine/threonine kinase activity GO Biological Processes -13.5008002 23 More
GO:0072503 cellular divalent inorganic cation homeostasis GO Biological Processes -7.40235615 16 More
GO:0072507 divalent inorganic cation homeostasis GO Biological Processes -10.6286093 21 More
GO:0072593 reactive oxygen species metabolic process GO Biological Processes -9.21564496 21 More
GO:0080164 regulation of nitric oxide metabolic process GO Biological Processes -19.7892071 27 More
GO:0086103 G protein-coupled receptor signaling pathway involved in heart process GO Biological Processes -5.67855223 6 More
GO:0090022 regulation of neutrophil chemotaxis GO Biological Processes -5.21154381 9 More
GO:0090023 positive regulation of neutrophil chemotaxis GO Biological Processes -3.41852381 6 More
GO:0090257 regulation of muscle system process GO Biological Processes -33.9441291 67 More
GO:0090497 mesenchymal cell migration GO Biological Processes -8.76593708 16 More
GO:0097485 neuron projection guidance GO Biological Processes -2.79075716 20 More
GO:0098771 inorganic ion homeostasis GO Biological Processes -12.1048319 31 More
GO:0098801 regulation of renal system process GO Biological Processes -10.5008143 14 More
GO:0099177 regulation of trans-synaptic signaling GO Biological Processes -15.1793607 60 More
GO:0110020 regulation of actomyosin structure organization GO Biological Processes -4.68299748 15 More
GO:0110110 positive regulation of animal organ morphogenesis GO Biological Processes -4.39105986 5 More
GO:0140352 export from cell GO Biological Processes -8.94733589 48 More
GO:0198738 cell-cell signaling by wnt GO Biological Processes -5.19226517 28 More
GO:1900046 regulation of hemostasis GO Biological Processes -39.0044157 31 More
GO:1900047 negative regulation of hemostasis GO Biological Processes -30.8008788 23 More
GO:1901224 positive regulation of NIK/NF-kappaB signaling GO Biological Processes -6.64954322 9 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901654 response to ketone GO Biological Processes -10.4509771 32 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1902074 response to salt GO Biological Processes -2.43585807 3 More
GO:1902622 regulation of neutrophil migration GO Biological Processes -4.86040077 10 More
GO:1902624 positive regulation of neutrophil migration GO Biological Processes -3.51698265 7 More
GO:1902903 regulation of supramolecular fiber organization GO Biological Processes -5.63791156 37 More
GO:1902905 positive regulation of supramolecular fiber organization GO Biological Processes -5.32876142 22 More
GO:1903034 regulation of response to wounding GO Biological Processes -34.9293555 38 More
GO:1903035 negative regulation of response to wounding GO Biological Processes -27.3379640 26 More
GO:1903522 regulation of blood circulation GO Biological Processes -44.9821911 79 More
GO:1903524 positive regulation of blood circulation GO Biological Processes -11.6803256 16 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903531 negative regulation of secretion by cell GO Biological Processes -17.4034654 36 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903793 positive regulation of anion transport GO Biological Processes -7.11509809 13 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:1904407 positive regulation of nitric oxide metabolic process GO Biological Processes -14.4967625 19 More
GO:1905114 cell surface receptor signaling pathway involved in cell-cell signaling GO Biological Processes -7.80587066 38 More
GO:1905952 regulation of lipid localization GO Biological Processes -40.6150331 64 More
GO:2000027 regulation of animal organ morphogenesis GO Biological Processes -7.86416421 22 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
GO:2000191 regulation of fatty acid transport GO Biological Processes -10.7141263 14 More
GO:2000193 positive regulation of fatty acid transport GO Biological Processes -7.51681508 10 More
GO:2000273 positive regulation of signaling receptor activity GO Biological Processes -8.61037442 14 More
GO:2001257 regulation of cation channel activity GO Biological Processes -11.2578208 33 More
KEGG pathways: 10 records
KEGG Description Category LogP Number of genes Detail
hsa04024 cAMP signaling pathway KEGG Pathway -7.78464854 30 More
hsa04066 HIF-1 signaling pathway KEGG Pathway -20.6790877 23 More
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04270 Vascular smooth muscle contraction KEGG Pathway -11.6218936 17 More
hsa04668 TNF signaling pathway KEGG Pathway -16.5384917 20 More
hsa04926 Relaxin signaling pathway KEGG Pathway -10.8215200 16 More
hsa04933 AGE-RAGE signaling pathway in diabetic complications KEGG Pathway -25.8646207 26 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05410 Hypertrophic cardiomyopathy KEGG Pathway -9.74858067 13 More
hsa05418 Fluid shear stress and atherosclerosis KEGG Pathway -23.1665561 27 More
Drug-Gene interaction
view
Related drugs: 12 records
Drug name Interaction type Source PMID View
atenolol PharmGKB 15188945 view
bevacizumab PharmGKB 27139155 view
budesonide NCI 7716352 view
celecoxib NCI 15539607 view
deferoxamine NCI 9112092 view
doxorubicin NCI 11589785 view
insulin NCI 11600523 view
irbesartan PharmGKB 15188945 view
lanreotide NCI 17051749 view
muraglitazar PharmGKB 18794727 view
tamoxifen NCI 8425178 view
thiouracil NCI 10967532 view
Related studies: 28 records
Molecular factor Omics type Application Objective MI type Reference
endothelin-1 proteomics complication[prognosis (bad)] acute myocardial infarction Lechleitner P et al. Clin Investig. 1992
endothelin-1 proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Stewart DJ et al. J Am Coll Cardiol. 1991
endothelin-1 proteomics medium predictor cardiovascular death[prognosis (bad)] acute myocardial infarction Omland T et al. Am J Cardiol. 1995
endothelin-1 proteomics adverse events[prognosis (bad)] acute myocardial infarction Setsuta K et al. Angiology. 1995
endothelin-1 proteomics heart failure[prognosis (bad)] acute myocardial infarction Tomoda H. Am Heart J. 1993
endothelin-1 proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Li SM et al. Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997
endothelin-1 proteomics puerarin[treatment (pharmacotherapy)] acute myocardial infarction Li SM et al. Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997
endothelin-1 proteomics left ventricular ejection fraction[other] acute myocardial infarction Battistelli S et al. Angiology. 1999
endothelin-1 proteomics morphine[treatment (pharmacotherapy)] acute ST elevation myocardial infarction Wang TL et al. Ann Emerg Med. 2001
endothelin-1 proteomics left ventricular remodeling[prognosis (bad)] acute anterior myocardial infarction Tsutamoto T et al. Eur Heart J. 2003
endothelin-1 proteomics adverse events[prognosis (bad)] acute ST elevation myocardial infarction Yip HK et al. Chest. 2005
endothelin-1 proteomics adverse events[prognosis (bad)] acute myocardial infarction Katayama T et al. Circ J. 2005
endothelin-1 proteomics no-reflow phenomenon[prognosis (bad)] acute myocardial infarction Niccoli G et al. Eur Heart J. 2006
endothelin-1 proteomics medium predictor adverse events[prognosis (bad)] acute myocardial infarction Behnes M et al. Clin Chem Lab Med. 2008
endothelin-1 proteomics death[prognosis (bad)] acute ST elevation myocardial infarction Eitel I et al. Am Heart J. 2010
endothelin-1 proteomics medium predictor no-reflow phenomenon[prognosis (bad)] acute ST elevation myocardial infarction Eitel I et al. Am Heart J. 2010
endothelin-1 proteomics good predictor microvascular obstruction[prognosis (bad)] acute ST elevation myocardial infarction Freixa X et al. Rev Esp Cardiol. 2011
endothelin-1 proteomics endothelial progenitor cell[other] acute ST elevation myocardial infarction Freixa X et al. Microvasc Res. 2011
endothelin-1 proteomics macrovascular disease[prognosis (bad)] acute myocardial infarction Li JL et al. J Int Med Res. 2012
endothelin-1 proteomics poor predictor myocardial reperfusion[prognosis (good)] acute ST elevation myocardial infarction Kilickesmez KO et al. Coron Artery Dis. 2015
endothelin-1 proteomics poor predictor major adverse cardiovascular events[prognosis (bad)] myocardial infarction Zhou BY et al. Per Med. 2018
endothelin-1 proteomics poor predictor no-reflow phenomenon[prognosis (bad)] acute ST elevation myocardial infarction Gao R et al. Med Sci Monit. 2018
endothelin-1 proteomics atorvastatin[treatment (pharmacotherapy)] acute anterior myocardial infarction Liu ZJ et al. Chin Med Sci J. 2018
endothelin-1 proteomics medium predictor acute type 2 myocardial infarction[diagnosis] acute type 2 myocardial infarction Horiuchi Y et al. Circulation. 2020
endothelin-1 proteomics cardiovascular adverse events[prognosis (bad)] acute non-ST elevation myocardial infarction Hartopo AB et al. Int J Vasc Med. 2020
endothelin-1 proteomics death[prognosis (bad)] acute myocardial infarction Omland T et al. Circulation. 1994
endothelin-1 proteomics major adverse cardiovascular events[prognosis (bad)] acute ST elevation myocardial infarction Setianto BY et al. Int J Cardiol. 2016
endothelin-1 proteomics cardiovascular death;heart failure hospitalization[prognosis (bad)] acute myocardial infarction Olivier A et al. Int J Cardiol. 2017
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